Welcome to
TopMatch
TopMatch calculates the similarity of protein structures.
TopMatch can be used for single protein chains and multichain complexes.
For a quick start, here are some examples you can try upon your first visit:
TopMatch can be used for single protein chains and multichain complexes.
For a quick start, here are some examples you can try upon your first visit:
| Single protein chains | Human hemoglobin and neuroglobin (140 + 150 residues) |
| Crystallographic asymmetric units | Histidine-tRNA synthetases (780 + 840 residues) |
| Biological assemblies | Complete ribosomes (11.000 + 6.500 residues; visualization may take some time…) |
| Query: | or Upload CIF file |
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| Target: |
For more information on input and results, please see TopMatch's Help page.
If you find TopMatch useful for your research, please cite the following reference:
Wiederstein & Sippl (2020).
TopMatch-web: pairwise matching of large assemblies of protein and nucleic acid chains in 3D.
Nucleic Acids Research, Web Server Issue 2020.
Wiederstein & Sippl (2020).
TopMatch-web: pairwise matching of large assemblies of protein and nucleic acid chains in 3D.
Nucleic Acids Research, Web Server Issue 2020.
The previous version of TopMatch-web is still available but will be retired soon.